The following murders were tried in Powhatan.

• 1871- Murder of Henry Braswell
• 1873- Murder of George Coffman
• 1874- murder of James E. Caraway
• 1876- murder commited by John Church
• 1876- murder committed by Mary Morrison
• 1877- murder committed by Kahn
• 1879- murder of child Issac Jones
• 1881- Murder of Thomas Miller
• 1883- Murder of Carlos Conklin
• 1884- Murder of Lewis Cissel
• 1889- Murder committed by Henry Brooks
• 1889- Murder of Charles Buster, defendant John McManus, George Roberts, and William Brooks
• 1890- murder of Thurza Baker (change of venue from Sharp County)
• 1890- murder of Will Smith
• 1891- Murder of Richard Ward
• 1895- Murder of Isaac Warren
• 1896- murder of Dr. Dorr
• 1897- Murder committed by Ben James
• 1898- Murder of Dave Donigan, committed by Dan Allen
• 1899- Murder of Bob Doyle, defendant Joe Mize
• 1899- murder of Charley Hale
• 1902- Murder of Bud Brightman
• 1902- Murder of George James
• 1908- murder of Albert Russel
• 1909- Murder of Alfred Oaks
• 1912- Murder of Harry Moore
• 1913- murder committed by Charles Hensley
• 1922- Murder of Bob Weir
• 1922- murder of Daily White
• 1924- murder, defendant Mabel Smith Lee
• 1930- murder committed by Byron Perkins
• 1932- murder committed by Rose Daily
• 1932- Murder of W.H. Waldron